Local slowdown of translation by nonoptimal codons promotes nascent-chain recognition by SRP in vivo
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/nsmb.2919.pdf
Reference57 articles.
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2. Spencer, P.S., Siller, E., Anderson, J.F. & Barral, J.M. Silent substitutions predictably alter translation elongation rates and protein folding efficiencies. J. Mol. Biol. 422, 328–335 (2012).
3. Xu, Y. et al. Non-optimal codon usage is a mechanism to achieve circadian clock conditionality. Nature 495, 116–120 (2013).
4. Dana, A. & Tuller, T. The effect of tRNA levels on decoding times of mRNA codons. Nucleic Acids Res. 42, 9171–9181 (2014).
5. Keenan, R.J., Freymann, D.M., Stroud, R.M. & Walter, P. The signal recognition particle. Annu. Rev. Biochem. 70, 755–775 (2001).
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