SOD1 aggregates in ALS: Cause, correlate or consequence?
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/nm1298_1362.pdf
Reference11 articles.
1. Rosen, D.R. et al. Mutations in the Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59–62 (1993).
2. Bruijn, L. et al. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science 261, 1851–1853 (1998).
3. Beckman, J.S., Carson, M., Smith, C.D. & Kuppenol, W.H. ALS, SOD, and peroxynitrite. Nature 364, 584 (1993).
4. Rabizadeh, S. et al. Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an anti-apoptotic gene to a pro-apoptotic gene: Studies in yeast and neural cells. Proc. Natl. Acad. Sci. USA 92, 3024–3028 (1995).
5. Shibata, N. et al. Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement. J. Neuropath. Exp. Neurol. 4, 481–490 (1996).
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