CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa-Reference-Cited by-同舟云学术

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CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa

Published:2015-08 Issue:8 Volume:23 Page:1308-1319
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Lipinski Daniel M,Barnard Alun R,Singh Mandeep S,Martin Chris,Lee Edward J,Davies Wayne I L,MacLaren Robert E

Funder

Fight for Sight

Wellcome Trust

Health Foundation

Medical Research Council

Royal College of Surgeons of Edinburgh

Oxford Stem Cell Institute

NIHR

Ophthalmology and Oxford Biomedical Research

Australian Research Council (ARC)

ARC

Royal Society University

Fulbright-Fight

University of Oxford

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference63 articles.

1. Increased expression of brain-derived neurotrophic factor preserves retinal function and slows cell death from rhodopsin mutation or oxidative damage;Okoye;J Neurosci,2003

2. Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa;McGee Sanftner;Mol Ther,2001

3. In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration;Buch;Mol Ther,2006

4. CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: the possible involvement of STAT3 pathway;Ji;Eur J Neurosci,2004

5. Cooperative effects of bcl-2 and AAV-mediated expression of CNTF on retinal ganglion cell survival and axonal regeneration in adult transgenic mice;Leaver;Eur J Neurosci,2006

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