Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes-Reference-Cited by-同舟云学术

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Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes

Published:2015-12 Issue:12 Volume:23 Page:1888-1898
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Moody Paul R,Sayers Edward J,Magnusson Johannes P,Alexander Cameron,Borri Paola,Watson Peter,Jones Arwyn T

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference69 articles.

1. Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants;Bien-Ly;J Exp Med,2014

2. Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle;Niewoehner;Neuron,2014

3. Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor;Wiley;Proc Natl Acad Sci USA,2013

4. Antibody-drug conjugates: basic concepts, examples and future perspectives;Casi;J Control Release,2012

5. Antibody-drug conjugate target selection: critical factors;Bander;Methods Mol Biol,2013

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