Huntingtin Haplotypes Provide Prioritized Target Panels for Allele-specific Silencing in Huntington Disease Patients of European Ancestry

Author:

Kay Chris,Collins Jennifer A,Skotte Niels H,Southwell Amber L,Warby Simon C,Caron Nicholas S,Doty Crystal N,Nguyen Betty,Griguoli Annamaria,Ross Colin J,Squitieri Ferdinando,Hayden Michael R

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference42 articles.

1. Multisource ascertainment of Huntington disease in Canada: prevalence and population at risk;Fisher;Mov Disord,2014

2. Epidemiology;Kay,2014

3. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes;The Huntington's Disease Collaborative Research Group;Cell,1993

4. A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats;Kremer;N Engl J Med,1994

5. Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats;Rubinsztein;Am J Hum Genet,1996

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3