Rapid desensitization of the TRH receptor and persistent desensitization of its constitutively active mutant

Author:

Zaltsman Ilona,Grimberg Hagit,Lupu-Meiri Monica,Lifschitz Ilana,Oron Yoram

Publisher

Wiley

Subject

Pharmacology

Reference20 articles.

1. Constitutively signaling G-protein-coupled receptors and human disease;ARVANITAKIS;Trends Endocrinol. Metabol.,1998

2. Real-time visualization of cellular redistribution of G protein-coupled receptor kinase 2 and β-arrestin 2 during homologous desensitization of substance P receptor;BARAK;J. Biol. Chem.,1999

3. Inverse agonist abolishes desensitization of a constitutively active mutant of thyrotropin-releasing hormone receptor: role of cellular calcium and protein kinase;GRIMBERG;C. Br. J. Pharmacol.,1999

4. A constitutively active mutant thyrotropin-releasing hormone receptor is chronically down-regulated in pituitary cells: Evidence using chlorodiazepoxide as a negative antagonist;HEINFLINK;Mol. Endocrinol.,1995

5. Constitutive activity of native thyrotropin-releasing hormone receptors revealed using a protein kinase C-responsive reporter gene;JINISI-PARIMOO;Endocrinology,1997

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