The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents

Author:

Rigo J-M,Hans G,Nguyen L,Rocher V,Belachew S,Malgrange B,Leprince P,Moonen G,Selak I,Matagne A,Klitgaard H

Publisher

Wiley

Subject

Pharmacology

Reference66 articles.

1. Zinc inhibition of gamma-aminobutyric acid(A) receptor function is decreased in the cerebral cortex during pilocarpine-induced status epilepticus;BANERJEE;J. Pharmacol. Exp. Ther.,1999

2. Glycine receptors: what gets in and why;BARRY;Clin. Exp. Pharmacol. Physiol.,1999

3. What is GABAergic inhibition? How is it modified in epilepsy;BERNARD;Epilepsia,2000

4. Structure and functions of inhibitory and excitatory glycine receptors;BETZ;Ann. N. Y. Acad. Sci.,1999

5. Levetiracetam (ucb LO59) affects in vitro models of epilepsy in CA3 pyramidal neurons without altering normal synaptic transmission;BIRNSTIEL;Naunyn Schmiedebergs Arch. Pharmacol.,1997

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