Glyoxalase activity in human erythrocytes and mouse lymphoma, liver and brain probed with hyperpolarized 13C-methylglyoxal

Author:

Shishmarev DmitryORCID,Kuchel Philip W.,Pagès GuilhemORCID,Wright Alan J.ORCID,Hesketh Richard L.,Kreis FelixORCID,Brindle Kevin M.ORCID

Funder

Department of Education and Training | Australian Research Council

Cancer Research UK

Publisher

Springer Science and Business Media LLC

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,Medicine (miscellaneous)

Reference37 articles.

1. Kalapos, M. P. Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications. Toxicol. Lett. 110, 145–175 (1999).

2. Dakin, H. D. & Dudley, H. W. An enzyme concerned with the formation of hydroxy acids from ketonic aldehydes. J. Biol. Chem. 14, 155–157 (1913).

3. Racker, E. The mechanism of action of glyoxalase. J. Biol. Chem. 190, 685–696 (1951).

4. Kalapos, M. P. Where does plasma methylglyoxal originate from? Diabetes Res. Clin. Pract. 99, 260–271 (2013).

5. Elliott, W. H. Methylglyoxal formation from aminoacetone by ox plasma. Nature 185, 467–468 (1960).

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