Dynamic contrast optical coherence tomography (DyC-OCT) for label-free live cell imaging-Reference-Cited by-同舟云学术

Dynamic contrast optical coherence tomography (DyC-OCT) for label-free live cell imaging

Published:2024-03-06 Issue:1 Volume:7 Page:
ISSN:2399-3642
Container-title:Communications Biology
language:en
Short-container-title:Commun Biol

Author:

Ren Chao^ORCID,Hao Senyue^ORCID,Wang Fei^ORCID,Matt Abigail,Amaral Marcello Magri^ORCID,Yang Daniel,Wang Leyao^ORCID,Zhou Chao^ORCID

Abstract

AbstractDynamic contrast optical coherence tomography (DyC-OCT), an emerging imaging method, utilizes fluctuation patterns in OCT signals to enhance contrast, thereby enabling non-invasive label-free volumetric live cell imaging. In this mini review, we explain the core concepts behind DyC-OCT image formation and its system configurations, serving as practical guidance for future DyC-OCT users. Subsequently, we explore its applications in delivering high-quality, contrast-enhanced images of cellular morphology, as well as in monitoring changes in cellular activity/viability assay experiments.

Funder

U.S. Department of Health & Human Services | NIH | National Institute of Biomedical Imaging and Bioengineering

U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s42003-024-05973-5.pdf

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