Empty virions in AAV8 vector preparations reduce transduction efficiency and may cause total viral particle dose-limiting side effects-Reference-Cited by-同舟云学术

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Empty virions in AAV8 vector preparations reduce transduction efficiency and may cause total viral particle dose-limiting side effects

Published:2014 Issue: Volume:1 Page:9
ISSN:2329-0501
Container-title:Molecular Therapy - Methods & Clinical Development
language:en
Short-container-title:Molecular Therapy - Methods & Clinical Development

Author:

Gao Kai,Li Mengxin,Zhong Li,Su Qin,Li Jia,Li Shaoyong,He Ran,Zhang Yu,Hendricks Gregory,Wang Junzhi,Gao Guangping

Publisher

Elsevier BV

Subject

Genetics,Molecular Biology,Molecular Medicine

Reference31 articles.

1. No evidence for tumorigenesis of AAV vectors in a large-scale study in mice;Bell;Mol Ther,2005

2. Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver;Bell;Mol Ther,2006

3. Assessing the potential for AAV vector genotoxicity in a murine model;Li;Blood,2011

4. Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cells;Hermonat;Proc Natl Acad Sci USA,1984

5. Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors;Snyder;Nat Genet,1997

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