Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG-Reference-Cited by-同舟云学术

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Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG

Published:2014-09-24 Issue:3 Volume:68 Page:153-157
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Gajadeera Chathurada,Willby Melisa J,Green Keith D,Shaul Pazit,Fridman Micha,Garneau-Tsodikova Sylvie,Posey James E,Tsodikov Oleg V

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja2014131.pdf

Reference35 articles.

1. Green, K. D . & Garneau-Tsodikova, S . Resistance in tuberculosis: what do we know and where can we go? Frontiers Microbiol. 4, 208 (2013).

2. Wong, E. B ., Cohen, K. A . & Bishai, W. R . Rising to the challenge: new therapies for tuberculosis. Trends Microbiol. 21, 493–501 (2013).

3. Klann, A. G ., Belanger, A. E ., Abanes-De Mello, A ., Lee, J. Y . & Hatfull, G. F . Characterization of the dnaG locus in Mycobacterium smegmatis reveals linkage of DNA replication and cell division. J. Bacteriol. 180, 65–72 (1998).

4. Gefter, M. L ., Hirota, Y ., Kornberg, T ., Wechsler, J. A . & Barnoux, C . Analysis of DNA polymerases II and 3 in mutants of Escherichia coli thermosensitive for DNA synthesis. Proc. Natl Acad. Sci. USA 68, 3150–3153 (1971).

5. van der Ende, A ., Baker, T. A ., Ogawa, T . & Kornberg, A . Initiation of enzymatic replication at the origin of the Escherichia coli chromosome: primase as the sole priming enzyme. Proc. Natl Acad. Sci. USA 82, 3954–3958 (1985).

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