The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/ni.2958.pdf
Reference43 articles.
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3. Kieper, W.C. & Jameson, S.C. Homeostatic expansion and phenotypic conversion of naive T cells in response to self peptide/MHC ligands. Proc. Natl. Acad. Sci. USA 96, 13306–13311 (1999).
4. Sprent, J. & Surh, C.D. Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells. Nat. Immunol. 12, 478–484 (2011).
5. Le Campion, A. et al. Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development. Blood 114, 1784–1793 (2009).
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