Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection-Reference-Cited by-同舟云学术

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Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

Published:2016-09-26 Issue:7624 Volume:538 Page:270-273
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

East-Seletsky Alexandra,O’Connell Mitchell R.,Knight Spencer C.,Burstein David,Cate Jamie H. D.,Tjian Robert,Doudna Jennifer A.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature19802.pdf

Reference34 articles.

1. van der Oost, J., Westra, E. R., Jackson, R. N. & Wiedenheft, B. Unravelling the structural and mechanistic basis of CRISPR-Cas systems. Nat. Rev. Microbiol. 12, 479–492 (2014)

2. Wright, A. V., Nuñez, J. K. & Doudna, J. A. Biology and applications of CRISPR systems: harnessing nature’s toolbox for genome engineering. Cell 164, 29–44 (2016)

3. Brouns, S. J. J. et al. Small CRISPR RNAs guide antiviral defense in prokaryotes. Science 321, 960–964 (2008)

4. Marraffini, L. A. & Sontheimer, E. J. CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA. Science 322, 1843–1845 (2008)

5. Garneau, J. E. et al. The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature 468, 67–71 (2010)

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