A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/s41557-018-0154-0.pdf
Reference37 articles.
1. Drake, P. M. & Rabuka, D. An emerging playbook for antibody–drug conjugates: lessons from the laboratory and clinic suggest a strategy for improving efficacy and safety. Curr. Opin. Chem. Biol. 28, 174–180 (2015).
2. Ueda, T. Next-generation optimized biotherapeutics—a review and preclinical study. Biochim. Biophys. Acta 1844, 2053–2057 (2014).
3. Hamann, P. R. et al. Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody–calicheamicin conjugate for treatment of acute myeloid leukemia. Bioconjug. Chem. 13, 47–58 (2002).
4. Wang, L., Amphlett, G., Blättler, W. A., Lambert, J. M. & Zhang, W. Structural characterization of the maytansinoid–monoclonal antibody immunoconjugate, huN901–DM1, by mass spectrometry. Protein Sci. 14, 2436–2446 (2005).
5. Lewis Phillips, G. D. et al. Targeting HER2-positive breast cancer with trastuzumab–DM1, an antibody–cytotoxic drug conjugate. Cancer Res. 68, 9280–9290 (2008).
Cited by 78 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Recombinant and Synthetic Affibodies Function Comparably for Modulating Protein Release;Cellular and Molecular Bioengineering;2024-09-12
2. Electrochemical chemoselective thiocarbamylation of late-stage Tyr-containing drugs and peptides;Science China Chemistry;2024-08-02
3. Synthetic electrochemistry for peptides;Current Opinion in Electrochemistry;2024-06
4. Recombinant and synthetic affibodies function comparably for modulating protein release;2024-05-11
5. Ultrafast Au(III)-Mediated Arylation of Cysteine;Journal of the American Chemical Society;2024-04-24
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3