A biologically stable DNAzyme that efficiently silences gene expression in cells
Author:
Funder
Simons Foundation
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/s41557-021-00645-x.pdf
Reference46 articles.
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3. Khvorova, A. & Watts, J. K. The chemical evolution of oligonucleotide therapies of clinical utility. Nat. Biotechnol. 35, 238–248 (2017).
4. Santoro, S. W. & Joyce, G. F. Mechanism and utility of an RNA-cleaving DNA enzyme. Biochemistry 37, 13330–13342 (1998).
5. Appaiahgari, M. B. & Vrati, S. DNAzyme-mediated inhibition of Japanese encephalitis virus replication in mouse brain. Mol. Ther. 15, 1593–1599 (2007).
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