Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction-Reference-Cited by-同舟云学术

Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction

Published:2021-12-16 Issue: Volume: Page:
ISSN:1755-4330
Container-title:Nature Chemistry
language:en
Short-container-title:Nat. Chem.

Author:

Crawshaw Rebecca,Crossley Amy E.,Johannissen Linus,Burke Ashleigh J.,Hay Sam^ORCID,Levy Colin,Baker David^ORCID,Lovelock Sarah L.^ORCID,Green Anthony P.^ORCID

Funder

RCUK | Biotechnology and Biological Sciences Research Council

RCUK | Engineering and Physical Sciences Research Council

University of Manchester, Faculty of Science and Engineering

RCUK | Medical Research Council

Publisher

Springer Science and Business Media LLC

Subject

General Chemical Engineering,General Chemistry

Link

https://www.nature.com/articles/s41557-021-00833-9.pdf

Reference63 articles.

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4. Siegel, J. B. et al. Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction. Science 329, 309–313 (2010).

5. Eiben, C. B. et al. Increased Diels–alderase activity through backbone remodelling guided by Foldit players. Nat. Biotechnol. 30, 190–192 (2012).

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