Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/s41557-021-00660-y.pdf
Reference88 articles.
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2. Neri, D. & Lerner, R. DNA-encoded chemical libraries: a selection system based on endowing organic compounds with amplifiable information. Ann. Rev. Biochem. 87, 24 (2018).
3. Goodnow, R. A. Jr., Dumelin, C. E. & Keefe, A. D. DNA-encoded chemistry: enabling the deeper sampling of chemical space. Nat. Rev. Drug Discov. 16, 131–147 (2017).
4. Favalli, N., Bassi, G., Scheuermann, J. & Neri, D. DNA-encoded chemical libraries—achievements and remaining challenges. FEBS Lett. 592, 2168–2180 (2018).
5. Dumelin, C. E. et al. A portable albumin binder from a DNA-encoded chemical library. Angew. Chem. Int. Ed. 47, 3196–3201 (2008).
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