Phase-specific RNA accumulation and duplex thermodynamics in multiphase coacervate models for membraneless organelles
Author:
Funder
National Aeronautics and Space Administration
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
https://www.nature.com/articles/s41557-022-00980-7.pdf
Reference48 articles.
1. Yewdall, N. A., André, A. A. M., Lu, T. & Spruijt, E. Coacervates as models of membraneless organelles. Curr. Opin. Colloid Interface Sci. 52, 101416 (2021).
2. Roden, C. & Gladfelter, A. S. RNA contributions to the form and function of biomolecular condensates. Nat. Rev. Mol. Cell Biol. 22, 183–195 (2021).
3. Zhang, H. et al. RNA controls polyQ protein phase transitions. Mol. Cell 60, 220–230 (2015).
4. Shin, Y. & Brangwynne, C. P. Liquid phase condensation in cell physiology and disease. Science 357, eaaf4382 (2017).
5. Cakmak, F. P., Choi, S., Meyer, M. O., Bevilacqua, P. C. & Keating, C. D. Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments. Nat. Commun. 11, 5949 (2020).
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