Targeting IL-7 reverses type 1 diabetes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd3805.pdf
Reference2 articles.
1. Penaranda, C. et al. IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc. Natl Acad. Sci. USA 25 Jun 2012 (doi:10.1073/pnas.1203692109)
2. Lee, L.-F. et al. Anti-IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function. Proc. Natl Acad. Sci. USA 25 Jun 2012 (doi:10.1073/pnas.1203795109)
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