An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs-Reference-Cited by-同舟云学术

An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs

Published:2011-12-02 Issue:6 Volume:19 Page:937-946
ISSN:1350-9047
Container-title:Cell Death & Differentiation
language:en
Short-container-title:Cell Death Differ

Author:

Garibaldi F,Cicchini C,Conigliaro A,Santangelo L,Cozzolino A M,Grassi G,Marchetti A,Tripodi M,Amicone L

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

http://www.nature.com/articles/cdd2011175.pdf

Reference33 articles.

1. Sanchez A, Fabregat I . Growth factor- and cytokine-driven pathways governing liver stemness and differentiation. World J Gastroenterol 2010; 16: 5148–5161.

2. Santangelo L, Marchetti A, Cicchini C, Conigliaro A, Conti B, Mancone C et al. The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4alpha. Hepatology 2011; 53: 2063–2074.

3. Graf T, Stadtfeld M . Heterogeneity of embryonic and adult stem cells. Cell Stem Cell 2008; 3: 480–483.

4. Colletti M, Cicchini C, Conigliaro A, Santangelo L, Alonzi T, Pasquini E et al. Convergence of Wnt signaling on the HNF4alpha-driven transcription in controlling liver zonation. Gastroenterology 2009; 137: 660–672.

5. Cicchini C, Filippini D, Coen S, Marchetti A, Cavallari C, Laudadio I et al. Snail controls differentiation of hepatocytes by repressing HNF4alpha expression. J Cell Physiol 2006; 209: 230–238.

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