Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/cdd201147.pdf
Reference31 articles.
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3. Schofield CJ, Ratcliffe PJ . Signalling hypoxia by HIF hydroxylases. Biochem Biophys Res Commun 2005; 338: 617–626.
4. Makino Y, Cao R, Svensson K, Bertilsson G, Asman M, Tanaka H et al. Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression. Nature 2001; 414: 550–554.
5. Makino Y, Uenishi R, Okamoto K, Isoe T, Hosono O, Tanaka H et al. Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): a negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells. J Biol Chem 2007; 282: 14073–14082.
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