Assessing the survival of transgenic plant DNA in the human gastrointestinal tract-Reference-Cited by-同舟云学术

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Assessing the survival of transgenic plant DNA in the human gastrointestinal tract

Published:2004-01-18 Issue:2 Volume:22 Page:204-209
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Netherwood Trudy,Martín-Orúe Susana M,O'Donnell Anthony G,Gockling Sally,Graham Julia,Mathers John C,Gilbert Harry J

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt934.pdf

Reference30 articles.

1. Gebhard, F. & Smalla, K. Transformation of Acinetobacter sp. strain BD413 by transgenic sugar beet DNA. Appl. Environ. Microbiol. 64, 1550–1554 (1998).

2. Einspanier, R. et al. The fate of forage plant DNA in farm animals: a collaborative case-study investigating cattle and chicken fed recombinant plant material. Eur. Food Res. Technol. 212, 129–134 (2001).

3. Schubbert, R., Lettmann, C. & Doerfler, W. Ingested foreign (phage M13) DNA survives transiently in the gastrointestinal tract and enters the bloodstream of mice. Mol. Gen. Genet. 242, 495–504 (1994).

4. Schubbert, R., Renz, D., Schmitz, B. & Doerfler, W. Foreign (M13) DNA ingested by mice reaches peripheral leukocytes, spleen, and liver via the intestinal wall mucosa and can be covalently linked to mouse DNA. Proc. Natl. Acad. Sci. USA 94, 961–966 (1997).

5. Schubbert, R., Hohlweg, U., Renz, D. & Doerfler, W. On the fate of orally ingested foreign DNA in mice: chromosomal association and placental transmission to the fetus. Mol. Gen. Genet. 259, 569–576 (1998).

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