Increased and prolonged human norovirus infection in RAG2/IL2RG deficient gnotobiotic pigs with severe combined immunodeficiency-Reference-Cited by-同舟云学术

Increased and prolonged human norovirus infection in RAG2/IL2RG deficient gnotobiotic pigs with severe combined immunodeficiency

Published:2016-04-27 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Lei Shaohua,Ryu Junghyun,Wen Ke,Twitchell Erica,Bui Tammy,Ramesh Ashwin,Weiss Mariah,Li Guohua,Samuel Helen,Clark-Deener Sherrie,Jiang Xi,Lee Kiho,Yuan Lijuan

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep25222.pdf

Reference57 articles.

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2. Suzuki, S. et al. Il2rg gene-targeted severe combined immunodeficiency pigs. Cell Stem Cell 10, 753–8 (2012).

3. Lee, K. et al. Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency. Proc Natl Acad Sci USA 111, 7260–5 (2014).

4. Li, P. et al. Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection. Xenotransplantation 22, 20–31 (2015).

5. Gaj, T., Gersbach, C. A. & Barbas, C. F. 3rd . ZFN, TALEN and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol 31, 397–405 (2013).

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