The first implementation of the NIMH FAST-FAIL approach to psychiatric drug development-Reference-Cited by-同舟云学术

The first implementation of the NIMH FAST-FAIL approach to psychiatric drug development

Published:2018-12-28 Issue:1 Volume:18 Page:82-84
ISSN:1474-1776
Container-title:Nature Reviews Drug Discovery
language:en
Short-container-title:Nat Rev Drug Discov

Author:

Krystal Andrew D.,Pizzagalli Diego A.,Mathew Sanjay J.,Sanacora Gerard,Keefe Richard,Song Allen,Calabrese Joseph,Goddard Andrew,Goodman Wayne,Lisanby Sarah H.,Smoski Moria,Weiner Richard,Iosifescu Dan,Nurnberger John,Szabo Steven,Murrough James,Shekhar Anantha,Potter William

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,General Medicine

Link

http://www.nature.com/articles/nrd.2018.222.pdf

Reference10 articles.

1. Kesselheim, A. S., Hwang, T. J. & Franklin, J. M. Two decades of new drug development for central nervous system disorders. Nat. Rev. Drug Discov. 14, 815–816 (2015).

2. Passchier, J. et al. Measuring drug-related receptor occupancy with positron emission tomography. Methods 27, 278–286 (2002).

3. Zheng, M. Q. et al. Synthesis and evaluation of 11CLY2795050 as a κ-opioid receptor antagonist radiotracer for PET imaging. J. Nucl. Med. 54, 455–463 (2013).

4. Lowe, S. L. et al. Safety, tolerability, and pharmacokinetic evaluation of single- and multiple-ascending doses of a novel kappa opioid receptor antagonist LY2456302 and drug interaction with ethanol in healthy subjects. J. Clin. Pharmacol. 54, 968–978 (2014).

5. Wiedemann, K. Biomarkers in development of psychotropic drugs. Dialogues Clin. Neurosci. 13, 225–234 (2011).

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