Tolerance is established in polyclonal CD4+ T cells by distinct mechanisms, according to self-peptide expression patterns-Reference-Cited by-同舟云学术

Tolerance is established in polyclonal CD4+ T cells by distinct mechanisms, according to self-peptide expression patterns

Published:2016-01-04 Issue:2 Volume:17 Page:187-195
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Malhotra Deepali^ORCID,Linehan Jonathan L,Dileepan Thamotharampillai,Lee You Jeong,Purtha Whitney E,Lu Jennifer V,Nelson Ryan W,Fife Brian T,Orr Harry T,Anderson Mark S,Hogquist Kristin A,Jenkins Marc K^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.3327.pdf

Reference62 articles.

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2. Wing, K. & Sakaguchi, S. Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nat. Immunol. 11, 7–13 (2010).

3. Semana, G., Gausling, R., Jackson, R.A. & Hafler, D.A. T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects. J. Autoimmun. 12, 259–267 (1999).

4. Moon, J.J. et al. Quantitative impact of thymic selection on Foxp3+ and Foxp3− subsets of self-peptide/MHC class II-specific CD4+ T cells. Proc. Natl. Acad. Sci. USA 108, 14602–14607 (2011).

5. Yu, W. et al. Clonal deletion prunes but does not eliminate self-specific αβ CD8+ T lymphocytes. Immunity 42, 929–941 (2015).

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