Helicobacter pylori generates cells with cancer stem cell properties via epithelial–mesenchymal transition-like changes

Author:

Bessède E,Staedel C,Acuña Amador L A,Nguyen P H,Chambonnier L,Hatakeyama M,Belleannée G,Mégraud F,Varon C

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference33 articles.

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2. Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH et al. Infection with Helicobacter pylori strains possessing CagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995; 55: 2111–2115.

3. Gwack J, Shin A, Kim CS, Ko KP, Kim Y, Jun JK et al. CagA-producing Helicobacter pylori and increased risk of gastric cancer: a nested case-control study in Korea. Br J Cancer 2006; 95: 639–641.

4. Murata-Kamiya N, Kurashima Y, Teishikata Y, Yamahashi Y, Saito Y, Higashi H et al. Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells. Oncogene 2007; 26: 4617–4626.

5. Amieva MR, Vogelmann R, Covacci A, Tompkins LS, Nelson WJ, Falkow S . Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science 2003; 300: 1430–1434.

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