Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis

Author:

Hill K S,Erdogan E,Khoor A,Walsh M P,Leitges M,Murray N R,Fields A P

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference64 articles.

1. Siegel R, Naishadham D, Jemal A . Cancer statistics, 2012. CA Cancer J Clin 2012; 62: 10–29.

2. Castagna M, Takai Y, Kaibuchi K, Sano K, Kikkawa U, Nishizuka Y . Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem 1982; 257: 7847–7851.

3. Kikkawa U, Takai Y, Tanaka Y, Miyake R, Nishizuka Y . Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters. J Biol Chem 1983; 258: 11442–11445.

4. Fields AP, Murray NR . Protein kinase C isozymes as therapeutic targets for treatment of human cancers. Adv Enzyme Regul 2008; 48: 166–178.

5. Cacace AM, Ueffing M, Philipp A, Han EK, Kolch W, Weinstein IB . PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase. Oncogene 1996; 13: 2517–2526.

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