CD99 suppresses osteosarcoma cell migration through inhibition of ROCK2 activity

Author:

Zucchini C,Manara M C,Pinca R S,De Sanctis P,Guerzoni C,Sciandra M,Lollini P-L,Cenacchi G,Picci P,Valvassori L,Scotlandi K

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference63 articles.

1. Levy R, Dilley J, Fox RI, Warnke R . A human thymus-leukemia antigen defined by hybridoma monoclonal antibodies. Proc Natl Acad Sci USA 1979; 76: 6552–6556.

2. Hahn JH, Kim MK, Choi EY, Kim SH, Sohn HW, Ham DI et al. CD99 (MIC2) regulates the LFA-1/ICAM-1-mediated adhesion of lymphocytes, and its gene encodes both positive and negative regulators of cellular adhesion. J Immunol 1997; 159: 2250–2258.

3. Bernard G, Breittmayer JP, de Matteis M, Trampont P, Hofman P, Senik A et al. Apoptosis of immature thymocytes mediated by E2/CD99. J Immunol 1997; 158: 2543–2550.

4. Bernard G, Raimondi V, Alberti I, Pourtein M, Widjenes J, Ticchioni M et al. CD99 (E2) upregulates alpha4beta1-dependent T-cell adhesion to inflamed vascular endothelium under flow conditions. Eur J Immunol 2000; 30: 3061–3065.

5. Bernard G, Zoccola D, Deckert M, Breittmayer JP, Aussel C, Bernard A . The E2 molecule (CD99) specifically triggers homotypic aggregation of CD4+ CD8+ thymocytes. J Immunol 1995; 154: 26–32.

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