The role of tranexamic acid in trauma — a life-saving drug with proven benefit
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
https://www.nature.com/articles/s41572-022-00367-5.pdf
Reference12 articles.
1. CRASH-2 trial collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 376, 23–32 (2010).
2. CRASH-2 collaborators. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet 377, 1096–1101 (2011).
3. CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. Lancet 394, 1713–1723 (2019).
4. Moore, E. E. et al. Trauma-induced coagulopathy. Nat. Rev. Dis. Primers 7, 30 (2021).
5. Roberts, I. et al. Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. Trials 18, 48 (2017).
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