Inflammatory thoughts about glioma gene therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/nm1199_1237.pdf
Reference7 articles.
1. Freeman, S.M., Ramesh, R. & Marrogi, A.J. Immune system in suicide-gene therapy. Lancet 349, 2–3 ( 1997).
2. Dewey, R.A. et al. Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials. Nature Med. 5, 1256–1263 (1999).
3. Kruse, C.A. et al. A rat glioma model, CNS-1, with invasive characteristics similar to those of human gliomas: A comparison to 9L gliosarcoma. J. Neuro-Oncol. 22, 191–200 ( 1994).
4. Yang, Y. et al. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc Natl. Acad. Sci. USA 91, 4407–4411 (1994).
5. Worgall, S. et al. Selective expansion of alveolar macrophages in vivo by adenovirus-mediated transfer of the murine granulocyte-macrophage colony-stimulating factor cDNA. Blood 93, 655– 666 (1999).
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