A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes-Reference-Cited by-同舟云学术

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A network-based phenotype mapping approach to identify genes that modulate drug response phenotypes

Published:2016-11-14 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Cairns Junmei,Ung Choong Yong,da Rocha Edroaldo Lummertz,Zhang Cheng,Correia Cristina,Weinshilboum Richard,Wang Liewei,Li Hu

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep37003.pdf

Reference49 articles.

1. Garnett, M. J. et al. Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature 483, 570–575 (2012).

2. Misale, S. et al. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature 486, 532–536 (2012).

3. Gottesman, M. M. Mechanisms of cancer drug resistance. Annu. Rev. Med. 53, 615–627 (2002).

4. Niederst, M. J. & Engelman, J. A. Bypass mechanisms of resistance to receptor tyrosine kinase inhibition in lung cancer. Sci. Signal. 6, re6 (2013).

5. Lawrence, M. S. et al. Discovery and saturation analysis of cancer genes across 21 tumour types. Nature 505, 495–501 (2014).

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