An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ-Reference-Cited by-同舟云学术

An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ

Published:2014-11-17 Issue:7534 Volume:517 Page:391-395
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Banks Alexander S.,McAllister Fiona E.,Camporez João Paulo G.,Zushin Peter-James H.,Jurczak Michael J.,Laznik-Bogoslavski Dina,Shulman Gerald I.,Gygi Steven P.,Spiegelman Bruce M.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature13887.pdf

Reference44 articles.

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2. Choi, J. H. et al. Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation. Nature 477, 477–481 (2011)

3. Yu, J. G. et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51, 2968–2974 (2002)

4. Tontonoz, P., Hu, E. & Spiegelman, B. M. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 79, 1147–1156 (1994)

5. Chawla, A., Schwarz, E. J., Dimaculangan, D. D. & Lazar, M. A. Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 135, 798–800 (1994)

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