CEACAM1 regulates TIM-3-mediated tolerance and exhaustion-Reference-Cited by-同舟云学术

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Published:2014-10-26 Issue:7534 Volume:517 Page:386-390
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Huang Yu-Hwa,Zhu Chen,Kondo Yasuyuki,Anderson Ana C.,Gandhi Amit,Russell Andrew,Dougan Stephanie K.,Petersen Britt-Sabina,Melum Espen,Pertel Thomas,Clayton Kiera L.,Raab Monika,Chen Qiang,Beauchemin Nicole,Yazaki Paul J.,Pyzik Michal,Ostrowski Mario A.,Glickman Jonathan N.,Rudd Christopher E.,Ploegh Hidde L.,Franke Andre,Petsko Gregory A.,Kuchroo Vijay K.,Blumberg Richard S.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature13848.pdf

Reference56 articles.

1. Monney, L. et al. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 415, 536–541 (2002)

2. Sabatos, C. A. et al. Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nature Immunol. 4, 1102–1110 (2003)

3. Sánchez-Fueyo, A. et al. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nature Immunol. 4, 1093–1101 (2003)

4. Jones, R. B. et al. Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J. Exp. Med. 205, 2763–2779 (2008)

5. Sakuishi, K. et al. Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J. Exp. Med. 207, 2187–2194 (2010)

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