Juno is the egg Izumo receptor and is essential for mammalian fertilization
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/nature13203.pdf
Reference50 articles.
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2. Gardner, A. J. & Evans, J. P. Mammalian membrane block to polyspermy: new insights into how mammalian eggs prevent fertilisation by multiple sperm. Reprod. Fertil. Dev. 18, 53–61 (2006)
3. Ikawa, M., Inoue, N., Benham, A. M. & Okabe, M. Fertilization: a sperm’s journey to and interaction with the oocyte. J. Clin. Invest. 120, 984–994 (2010)
4. Inoue, N., Ikawa, M., Isotani, A. & Okabe, M. The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs. Nature 434, 234–238 (2005)
5. Le Naour, F., Rubinstein, E., Jasmin, C., Prenant, M. & Boucheix, C. Severely reduced female fertility in CD9-deficient mice. Science 287, 319–321 (2000)
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