HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia-Reference-Cited by-同舟云学术

HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia

Published:2014-08-24 Issue:7521 Volume:514 Page:242-246
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Arlet Jean-Benoît,Ribeil Jean-Antoine,Guillem Flavia,Negre Olivier,Hazoume Adonis,Marcion Guillaume,Beuzard Yves,Dussiot Michaël,Moura Ivan Cruz,Demarest Samuel,de Beauchêne Isaure Chauvot,Belaid-Choucair Zakia,Sevin Margaux,Maciel Thiago Trovati,Auclair Christian,Leboulch Philippe,Chretien Stany,Tchertanov Luba,Baudin-Creuza Véronique,Seigneuric Renaud,Fontenay Michaela,Garrido Carmen,Hermine Olivier,Courtois Geneviève

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature13614.pdf

Reference31 articles.

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2. Ginzburg, Y. & Rivella, S. β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism. Blood 118, 4321–4330 (2011)

3. Yuan, J. et al. Accelerated programmed cell death (apoptosis) in erythroid precursors of patients with severe β-thalassemia (Cooley’s anemia). Blood 82, 374–377 (1993)

4. Mathias, L. A. et al. Ineffective erythropoiesis in β-thalassemia major is due to apoptosis at the polychromatophilic normoblast stage. Exp. Hematol. 28, 1343–1353 (2000)

5. Centis, F. et al. The importance of erythroid expansion in determining the extent of apoptosis in erythroid precursors in patients with β-thalassemia major. Blood 96, 3624–3629 (2000)

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