Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer-Reference-Cited by-同舟云学术

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

Published:2014-07-02 Issue:7516 Volume:513 Page:110-114
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Saha Supriya K.,Parachoniak Christine A.,Ghanta Krishna S.,Fitamant Julien,Ross Kenneth N.,Najem Mortada S.,Gurumurthy Sushma,Akbay Esra A.,Sia Daniela,Cornella Helena,Miltiadous Oriana,Walesky Chad,Deshpande Vikram,Zhu Andrew X.,Hezel Aram F.,Yen Katharine E.,Straley Kimberly S.,Travins Jeremy,Popovici-Muller Janeta,Gliser Camelia,Ferrone Cristina R.,Apte Udayan,Llovet Josep M.,Wong Kwok-Kin,Ramaswamy Sridhar,Bardeesy Nabeel

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature13441.pdf

Reference38 articles.

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2. Hezel, A. F., Deshpande, V. & Zhu, A. X. Genetics of biliary tract cancers and emerging targeted therapies. J. Clin. Oncol. 28, 3531–3540 (2010)

3. Razumilava, N. & Gores, G. J. Cholangiocarcinoma. Lancet http://dx.doi.org/10.1016/S0140-6736(13)61903-0 (2014)

4. Voss, J. S. et al. Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions. Hum. Pathol. 44, 1216–1222 (2013)

5. Wang, P. et al. Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene 32, 3091–3100 (2013)

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