Author:
Friedman Joseph H,Beck James C,Chou Kelvin L,Clark Gracia,Fagundes Christopher P,Goetz Christopher G,Herlofson Karen,Kluger Benzi,Krupp Lauren B,Lang Anthony E,Lou Jao-Shin,Marsh Laura,Newbould Anne,Weintraub Daniel
Abstract
Abstract
Fatigue is a severe problem for many people living with Parkinson’s disease (PD). Best estimates suggest that more than 50% of patients experience this debilitating symptom. Little is known about its etiology or treatment, making the understanding of fatigue a true unmet need. As part of the Parkinson’s Disease Foundation Community Choice Research Program, patients, caregivers, and scientists attended a symposium on fatigue on 16 and 17 October 2014. We present a summary of that meeting, reviewing what is known about the diagnosis and treatment of fatigue, its physiology, and what we might learn from multiple sclerosis (MS), depression, and cancer—disorders in which fatigue figures prominently too. We conclude with focused recommendations to enhance our understanding and treatment of this prominent problem in PD.
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Neurology (clinical),Neurology
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