Author:
Okaty Benjamin W.,Commons Kathryn G.,Dymecki Susan M.
Publisher
Springer Science and Business Media LLC
Reference331 articles.
1. Erspamer, V. & Asero, B. Identification of enteramine, the specific hormone of the enterochromaffin cell system, as 5-hydroxytryptamine. Nature 169, 800–801 (1952). This paper is the first to recognize that enteramine and 5-HT are the same chemical.
2. Twarog, B. M. & Page, I. H. Serotonin content of some mammalian tissues and urine and a method for its determination. Am. J. Physiol. 175, 157–161 (1953). This paper is the first to demonstrate that 5-HT is present in vertebrate brain extracts.
3. Vialli, M. & Erspamer, V. Ricerche sul secreto delle cellule enterocromaffini. Z. Zellforsch. Mikrosk. Anat. 27, 81–99 (1937). This paper presents the first reported discovery of ‘enteramine’ (5-HT), a chemical that was isolated from enterochromaffin cells in the rabbit gut mucosa and was shown to possess smooth-muscle-contracting properties.
4. Rapport, M. M., Green, A. A. & Page, I. H. Crystalline serotonin. Science 108, 329–330 (1948). This paper presents the first reported discovery of 5-HT, which was isolated from beef serum and shown to act as a vasoconstrictor.
5. Rapport, M. M. Serum vasoconstrictor (serotonin) the presence of creatinine in the complex; a proposed structure of the vasoconstrictor principle. J. Biol. Chem. 180, 961–969 (1949). This paper is the first to describe the chemical structure of 5-HT.
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