Emerging roles for CNS fibroblasts in health, injury and disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
https://www.nature.com/articles/s41583-021-00525-w.pdf
Reference127 articles.
1. Vanlandewijck, M. et al. A molecular atlas of cell types and zonation in the brain vasculature. Nature 554, 475–480 (2018). Identifies molecularly distinct fibroblast cell types associated with the mouse vasculature, providing some of the first evidence of CNS fibroblast heterogeneity.
2. Dani, N. et al. A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell 184, 3056–3074.e21 (2021). Describes for the first time the molecular heterogeneity of choroid plexus fibroblasts across the three ventricles, providing important insight into potential fibroblast function in the choroid plexus.
3. Rustenhoven, J. et al. Functional characterization of the dural sinuses as a neuroimmune interface. Cell 184, 1000–1016.e27 (2021).
4. Dorrier, C. E. et al. CNS fibroblasts form a fibrotic scar in response to immune cell infiltration. Nat. Neurosci. 24, 234–244 (2021). First use of inducible lineage tracing to show that scar-forming cells in an animal model of MS are CNS fibroblasts and not pericytes or vSMCs.
5. Liu, J. et al. A human cell type similar to murine central nervous system perivascular fibroblasts. Exp. Cell Res. 402, 112576 (2021).
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