The future of stem cell therapies for Parkinson disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
http://www.nature.com/articles/s41583-019-0257-7.pdf
Reference161 articles.
1. Henchcliffe, C. & Parmar, M. Repairing the brain: cell replacement using stem cell-based technologies. J. Parkinsons Dis. 8, S131–S137 (2018).
2. Barker, R. A., Barrett, J., Mason, S. L. & Bjorklund, A. Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson’s disease. Lancet Neurol. 12, 84–91 (2013). A systematic review of transplantation trials using human fetal tissue and that includes critical reappraisal of data from the clinical trials.
3. Kriks, S. et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease. Nature 480, 547–551 (2011). The first protocol of bona fide hPSC-derived mesDA neurons via floorplate progenitors with good in vivo survival and functional maturation.
4. Kirkeby, A. et al. Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions. Cell Rep. 1, 703–714 (2012).
5. Doi, D. et al. Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation. Stem Cell Rep. 2, 337–350 (2014).
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