Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis-Reference-Cited by-同舟云学术

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

Published:2003-04-14 Issue:5 Volume:9 Page:533-539
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Pym Alexander S.,Brodin Priscille,Majlessi Laleh,Brosch Roland,Demangel Caroline,Williams Ann,Griffiths Karen E.,Marchal Gilles,Leclerc Claude,Cole Stewart T.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm859.pdf

Reference45 articles.

1. Fine, P.E.M. Variation in protection by BCG: implications of and for heterologous immunity. Lancet 346, 1339–1345 (1995).

2. Brandt, L. et al. Failure of the Mycobacterium bovis BCG vaccine: some species of environmental mycobacteria block multiplication of BCG and induction of protective immunity to tuberculosis. Infect. Immun. 70, 672–678 (2002).

3. Harboe, M., Oettinger, T., Wiker, H.G., Rosenkrands, I. & Andersen, P. Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG. Infect. Immun. 64, 16–22 (1996).

4. Behr, M.A. et al. Comparative genomics of BCG vaccines by whole-genome DNA microarrays. Science 284, 1520–1523 (1999).

5. Gordon, S.V. et al. Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays. Molec. Microbiol. 32, 643–656 (1999).

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