Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs-Reference-Cited by-同舟云学术

Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs

Published:2015-09-24 Issue:1 Volume:5 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Qian Lili,Tang Maoxue,Yang Jinzeng,Wang Qingqing,Cai Chunbo,Jiang Shengwang,Li Hegang,Jiang Ke,Gao Pengfei,Ma Dezun,Chen Yaoxing,An Xiaorong,Li Kui,Cui Wentao

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep14435.pdf

Reference54 articles.

1. Grobet, L. et al. A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nat Genet 17, 71–74 (1997).

2. McPherron, A. C. & Lee, S. J. Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci USA 94, 12457–12461 (1997).

3. Lee, S. J. & McPherron, A. C. Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci USA 98, 9306–9311 (2001).

4. Zimmers, T. A. et al. Induction of cachexia in mice by systemically administered myostatin. Science 296, 1486–1488 (2002).

5. Hill, J. J., Qiu, Y., Hewick, R. M. & Wolfman, N. M. Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains. Mol Endocrinol 17, 1144–1154 (2003).

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