A glycolytic shift in Schwann cells supports injured axons
Author:
Funder
Muscular Dystrophy Association
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
https://www.nature.com/articles/s41593-020-0689-4.pdf
Reference79 articles.
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2. Figley, M. D. & DiAntonio, A. The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease. Curr. Opin. Neurobiol. 63, 59–66 (2020).
3. Krauss, R., Bosanac, T., Devraj, R., Engber, T. & Hughes, R. O. Axons matter: the promise of treating neurodegenerative disorders by targeting SARM1-mediated axonal degeneration. Trends Pharmacol. Sci. 41, 281–293 (2020).
4. Yang, J. et al. Pathological axonal death through a MAPK cascade that triggers a local energy deficit. Cell 160, 161–176 (2015).
5. Walker, L. et al. MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.eLife 6, e22540 (2017).
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