Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease-Reference-Cited by-同舟云学术

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Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease

Published:2021-02-08 Issue:3 Volume:24 Page:343-354
ISSN:1097-6256
Container-title:Nature Neuroscience
language:en
Short-container-title:Nat Neurosci

Author:

Guttikonda Sudha R.,Sikkema Lisa^ORCID,Tchieu Jason^ORCID,Saurat Nathalie,Walsh Ryan M.,Harschnitz Oliver^ORCID,Ciceri Gabriele,Sneeboer Marjolein,Mazutis Linas,Setty Manu^ORCID,Zumbo Paul,Betel Doron^ORCID,de Witte Lot D.,Pe’er Dana^ORCID,Studer Lorenz^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

Tri-I Starr Stem Cell Scholar fellowship

Glenn/AFAR Postdoctoral Fellowship

NYSTEM fellowship

EMBO Fellowship

U.S. Department of Health & Human Services | NIH | Office of Extramural Research, National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

General Neuroscience

Link

http://www.nature.com/articles/s41593-020-00796-z.pdf

Reference65 articles.

1. Keren-Shaul, H. et al. A unique microglia type associated with restricting development of Alzheimer’s disease. Cell 169, 1276–1290 (2017).

2. Lecours, C. et al. Microglial implication in Parkinson’s disease: loss of beneficial physiological roles or gain of inflammatory functions? Front. Cell. Neurosci. https://doi.org/10.3389/fncel.2018.00282 (2018).

3. Geloso, M. C. et al. The dual role of microglia in ALS: mechanisms and therapeutic approaches. Front. Aging Neurosci. https://doi.org/10.3389/fnagi.2017.00242 (2017).

4. Clarke, L. E. et al. Normal aging induces A1-like astrocyte reactivity. Proc. Natl Acad. Sci. USA 115, E1896–E1905 (2018).

5. Liddelow, S. A. et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature 541, 481–487 (2017).

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