Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

Author:

Wheeler D L,Huang S,Kruser T J,Nechrebecki M M,Armstrong E A,Benavente S,Gondi V,Hsu K-T,Harari P M

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference30 articles.

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2. Benavente S, Huang S, Armstrong E, Chi A, Chinnaiyan P, Harari PM . (2004). Establishment of acquired resistance to epidermal growth factor receptor (EGFR) inhibitors in human tumor cell lines. AACR Meeting Abstracts 2004: 1230a.

3. Bonner JA, Harari PM, Giralt J, Azarnia N, Shin DM, Cohen RB et al. (2006). Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354: 567–578.

4. Christensen JG, Schreck R, Burrows J, Kuruganti P, Chan E, Le P et al. (2003). A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo. Cancer Res 63: 7345–7355.

5. Ciardiello F, Bianco R, Caputo R, Caputo R, Damiano V, Troiani T et al. (2004). Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy. Clin Cancer Res 10: 784–793.

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