Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc200845.pdf
Reference42 articles.
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3. Chen L, Gilkes DM, Pan Y, Lane WS, Chen J . (2005). ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage. EMBO J 24: 3411–3422.
4. Chen S, Xu Y, Yuan X, Bubley GJ, Balk SP . (2006). Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proc Natl Acad Sci USA 103: 15969–15974.
5. Cinar B, De Benedetti A, Freeman MR . (2005). Post-transcriptional regulation of the androgen receptor by mammalian target of rapamycin. Cancer Res 65: 2547–2553.
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