Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution-Reference-Cited by-同舟云学术

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

Published:2007-01-07 Issue:2 Volume:39 Page:218-225
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Helgason Agnar,Pálsson Snæbjörn,Thorleifsson Gudmar,Grant Struan F A,Emilsson Valur,Gunnarsdottir Steinunn,Adeyemo Adebowale,Chen Yuanxiu,Chen Guanjie,Reynisdottir Inga,Benediktsson Rafn,Hinney Anke,Hansen Torben,Andersen Gitte,Borch-Johnsen Knut,Jorgensen Torben,Schäfer Helmut,Faruque Mezbah,Doumatey Ayo,Zhou Jie,Wilensky Robert L,Reilly Muredach P,Rader Daniel J,Bagger Yu,Christiansen Claus,Sigurdsson Gunnar,Hebebrand Johannes,Pedersen Oluf,Thorsteinsdottir Unnur,Gulcher Jeffrey R,Kong Augustine,Rotimi Charles,Stefánsson Kári

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng1960.pdf

Reference30 articles.

1. Grant, S.F.A. et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat. Genet. 38, 320–323 (2006).

2. Rotimi, C.N. et al. In search of susceptibility genes for type 2 diabetes in West Africa: the design and results of the first phase of the AADM study. Ann. Epidemiol. 11, 51–58 (2001).

3. Florez, J.C. et al. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N. Engl. J. Med. 355, 241–250 (2006).

4. Groves, C.J. et al. Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes 55, 2640–2644 (2006).

5. Sabeti, P.C. et al. Detecting recent positive selection in the human genome from haplotype structure. Nature 419, 832–837 (2002).

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