Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep17350.pdf
Reference50 articles.
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2. Rosen, A. B. et al. Finding fluorescent needles in the cardiac haystack: tracking human mesenchymal stem cells labeled with quantum dots for quantitative in vivo three-dimensional fluorescence analysis. Stem Cells 25, 2128–2138 (2007).
3. Prasad, K. M., Smith, R. S., Xu, Y. & French, B. A. A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction. J Gene Med 13, 333–341 (2011).
4. Ambrosi, C. M. et al. Distribution of donor cells alters energy requirements for optogenetic control of the heart. Heart Rhythm 10, S96 (2013).
5. Prasad, K. M., Xu, Y., Yang, Z., Acton, S. T. & French, B. A. Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution. Gene Ther 18, 43–52 (2011).
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