Influence of single-nucleotide polymorphisms on deferasirox Ctrough levels and effectiveness
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,Genetics,Molecular Medicine
Link
http://www.nature.com/articles/tpj201465.pdf
Reference57 articles.
1. Cappellini MD, Cohen A, Piga A, Bejaoui M, Perrotta S, Agaoglu L et al. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia. Blood 2006; 107: 3455–3462.
2. Nisbet-Brown E, Olivieri NF, Giardina PJ, Grady RW, Neufeld EJ, Sechaud R et al. Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet 2003; 361: 1597–1602.
3. Waldmeier F, Bruin GJ, Glaenzel U, Hazell K, Sechaud R, Warrington S et al. Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state. Drug Metab Dispos 2010; 38: 808–816.
4. Bruin GJ, Faller T, Wiegand H, Schweitzer A, Nick H, Schneider J et al. Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats. Drug Metab Dispos 2008; 36: 2523–2538.
5. Taher A, Hershko C, Cappellini MD . Iron overload in thalassaemia intermedia: reassessment of iron chelation strategies. Br J Haematol 2009; 147: 634–640.
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