A combined high CYP2D6-CYP2C19 metabolic capacity is associated with the severity of suicide attempt as measured by objective circumstances-Reference-Cited by-同舟云学术

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A combined high CYP2D6-CYP2C19 metabolic capacity is associated with the severity of suicide attempt as measured by objective circumstances

Published:2014-08-12 Issue:2 Volume:15 Page:172-176
ISSN:1470-269X
Container-title:The Pharmacogenomics Journal
language:en
Short-container-title:Pharmacogenomics J

Author:

Peñas-Lledó E,Guillaume S,Naranjo M E G,Delgado A,Jaussent I,Blasco-Fontecilla H,Courtet P,LLerena A

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine

Link

http://www.nature.com/articles/tpj201442.pdf

Reference37 articles.

1. Zackrisson AL, Lindblom B, Ahlner J . High frequency of occurrence of CYP2D6 gene duplication/multiduplication indicating ultrarapid metabolism among suicide cases. Clin Pharmacol Ther 2010; 88: 354–359.

2. Peñas-Lledó EM, Dorado P, Aguera Z, Gratacos M, Estivill X, Fernandez-Aranda F et al. High risk of lifetime history of suicide attempts among CYP2D6 ultrarapid metabolizers with eating disorders. Mol Psychiatry 2011; 16: 691–692.

3. Stingl JC, Viviani R . CYP2D6 in the brain: impact on suicidality. Clin Pharmacol Ther 2011; 89: 352–353.

4. Peñas-Lledó EM, Blasco-Fontecilla H, Dorado P, Vaquero-Lorenzo C, Baca-Garcia E, Llerena A . CYP2D6 and the severity of suicide attempts. Pharmacogenomics 2012; 13: 179–184.

5. Llerena A, Dorado P, Peñas-Lledó EM . Pharmacogenetics of debrisoquine and its use as a marker for CYP2D6 hydroxylation capacity. Pharmacogenomics 2009; 10: 17–28.

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